Prognosis negative

E.B. White in the introduction to his 1977 collection of essays, remembering his 1948 “Here Is New York” (his observation more true now, perhaps, than ever):

Some, like “Here Is New York,” have been seriously affected by the passage of time and now stand as period pieces. I wrote about New York in the summer of 1948, during a hot spell. The city I described has disappeared, and another city has emerged in its place — one that I’m not familiar with. … The last time I visited New York, it seemed to have suffered a personality change, as though it had a brain tumor as yet undetected.